Pick up any 2 of the following items in a single run: Bob's Rotten Head, Dead Cat, Cricket's Head, Tammy's HeadĬollect 2 of either Roid Rage, The Virus, Growth Hormones, Experimental Treatment or Speed BallĬollect three of the following in a single run: Signs of the Zodiac, Magic 8 Ball, Tiny Planet, and Crystal Ballĭonate to a Battery Bum until he pays out with an item (4.

Then spend every single one of them in a single runĮdit: After looking at the comments, I've decided to add the 'collect these items in one run' achievements, as well as some other ones. Kill Hornfel before he can escape after breaking his minecart (PC) Reset 7 times in a row / (Switch, PS4) Get a minus 10-win streakĬollect 10 'tears up' items or pills in one runĮnter every Shop from chapter 1 through chapter 3 in one runĭie to your own explosion from Ipecac, Bob's Rotten Head, or Horf! pillīlow up The Siren's skull after defeating herĪllow Baby Plum to escape instead of defeating her Get a 5-win streak in the daily challengesĬomplete 7 daily challenges (by touching the trophy at the end)ĭefeat The Lamb without taking hearts, coins, and bombs through an entire run Participate in 31 daily challenges (they don't have to be consecutive it will still count if you die in the first room) Get a 5-win streak (3 in Rep), using a different character for each winĬomplete a Victory Lap, defeating The Lamb Use Blank Card while holding XIX - The Sun Make a Super Meat Boy by picking up 4 Cube of Meats in one runĭefeat Mom, Mom's Heart or It Lives using The Bible Make a Super Bandage Girl by picking up 4 Balls of Bandages in one run Isaacs new quest takes him to unknown places hes never been, filled with horrible new enemies and bosses, weapon combos youve never synergized before and. Here's a link to my Isaac: Repentance beginner's guide. These are for achievements that aren't exactly obvious, and that you probably won't know about through regular gameplay. I've made a list of all the 'one-off' or niche achievements.

Binding of isaac rebirth achievements